Blind Biopsy Can Miss Diagnoses and May Add to Treatment Delays

In the evaluation of abnormal uterine bleeding (AUB), blind biopsy alone can miss diagnoses of up to 18% of patients and may add to treatment delays.


If cancer occupies less than 50%

of the surface area of the endometrial cavity, the cancer can be missed by a blind biopsy1

Blind biopsy alone could miss the diagnosis of focal lesions in

up to 18% of patients2

Use Direct Visualization at Point-of-Care

In premenopausal ovulatory women with AUB,
hysteroscopy will detect an anatomical structural lesion

in 65-80% of patients3

Diagnose More Accurately

Endosee allows you to diagnose uterine focal pathology more accurately than endometrial biopsy alone.

Sensitivity for diagnosing polyps1

Blind Biopsy
11%

Hysteroscopy
89%

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Sensitivity for diagnosing myomas1

Blind Biopsy
13%

Hysteroscopy
100%

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Sensitivity for diagnosing hyperplasia1

Blind Biopsy
25%

Hysteroscopy
74%

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Save Time and Resources

Office
Hysteroscopy VS
Diagnostic Hysteroscopy
In the OR

Office hysteroscopy can help decrease the rate of diagnostic hysteroscopy in the OR under anesthesia5

Cost-Effectiveness of Office Hysteroscopy – Study

Savings of
$1,498
Per Patient

75 of 130 women who underwent diagnostic office hysteroscopy for abnormal bleeding did not need to undergo hysteroscopy in the OR. This represents estimated savings of $1,498 per patient.5

Cost-Effectiveness of Office Hysteroscopy – Study

Feedback from 106 Endosee Trials with 42 Clinicians

Speed of Procedure:

  • Average time per procedure: Less than 3 minutes
  • Average time doctors were in the exam room per procedure: Less than 13 minutes
  • “With Endosee, we can turn over the room in 20 minutes” – Physician feedback

Visualization:

  • Cases in which visualization was reported “excellent” or “adequate”* 98%
  • Procedures with anatomical challenges in seeing the complete uterine cavity+ 9%

*Remaining 2% of procedures were stopped prematurely due to patient request.
+Severe obstruction due to Asherman’s syndrome, multiple polyps or fibroids, or if severely anteflexed uterine position.

Patient Comfort:

  • Patients reporting no discomfort or mild discomfort* 91.5%
  • Procedures in which NSAIDs were used 44.2%
  • Procedures in which a paracervical block was used 37.5%
  • Procedures in which a slight dilation was used 45.1%

*Discomfort reported was mostly due to uterine distention

References

1. ACOG Practice Bulletin Number 128. 2. Goldstein S, Zeltser I, Horan C, et al. Am J Obstet Gynecol. 1997;177:102-108. 3. Isaacson K. Curr Opin Obstet Gynecol. 2002;14:381-385. 4. Garcia A. OBG Manage. 2013;25:44-48. 5. Moawad N, Santamaria E, Johnson M, Shuster J. JSLS. 2014;18:1-5.

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