Clinical Study

Diagnostic hysteroscopy is more accurate than SIS and TVUS in assessing endometrial pathology

Grimbizis GF, Tsolakidis D, Mikos T, et al. Fertil Steril. 2010; 94:2721-2725.

A study of 105 women compared diagnostic hysteroscopy (DH), saline infusion sonohysterography (SIS), and transvaginal ultrasound (TVUS) in the assessment of endometrial pathology.

  • DH was the most accurate technique in the diagnosis of all endometrial pathologies (AUC=0.953) vs SIS (AUC=0.759) and TVUS (AUC=0.725)
  • DH had superior diagnostic performance vs. SIS (P<.001) and TVUS (P<0.001)
  • DH more accurately diagnosed endometrial diseases and intracavitary masses

Additionally, diseases of the endometrium (eg, hyperplasia and cancer) cannot be distinguished by SIS or TVUS.

Comparison of TVUS,
SIS, DH – Study

Click to View Disease State Results
  • aAny Path
  • bMyomas/Polyps
  • cMyomas
  • dPolyps
  • eDiseases
  • fStruc. Abnorm.